These Top 5 Prostate Supplements Can Help Reduce the Frequent Urinary Urges Waking You Up Every Night
We have identified the key factors to look for in a top-notch prostate health supplement and how you can spot the scams
If you are over 50 and sudden bladder urges throughout the night are depriving you of sleep, the underlying cause is probably not that extra glass of water you had too close to bedtime. An enlarged prostate is likely to blame.
For men in their 20s and 30s, the prostate is typically the size of a walnut. However, starting in the early 40s, this tiny reproductive organ begins to grow, often reaching the size of a lemon or even a grapefruit by age 60. As it expands, the gland presses against the bladder wall, causing frequent urinary urges and the sensation of a constantly full bladder. In addition, because the prostate surrounds the urethra, it restricts the flow of urine as it enlarges, resulting in a weak, dribbling stream and even issues in the romantic department.
While an enlarged prostate is a natural consequence of aging, free radical damage caused by environmental and dietary factors can accelerate prostate growth. However, a diet rich in antioxidants and a well-rounded supplement can help reduce frequent urination and protect against BPH issues as you grow older.
How Can You Tell Which Products Are Good or Bad for the Prostate?
Recent studies have indicated that more than half of men over age 50 and 80% of men over age 70 suffer from an enlarged prostate. Perhaps it is no surprise, then, that public demand for prostate supplements is growing rapidly.
And yet, not all supplements are created equal. The fast-growing market for prostate support products has lured many companies to release ineffective supplements containing filler ingredients with little or no proof of efficacy. That’s why our staff decided to review all the most popular prostate formulas today and evaluate them for safety and effectiveness. We will show you what to look for, what to avoid, and which products we determined to be the best.
In our analysis, we noticed a number of companies making exaggerated claims about the level of relief their products can provide, not all of which are likely. What kind of results can you realistically expect from a prostate supplement?
In our analysis, we noticed a number of companies making exaggerated claims about the level of relief their products can provide, not all of which are likely. What kind of results can you realistically expect from a prostate supplement?
When Will You See Results?
The ingredients in most prostate health products can provide some noticeable relief within 30 days. However, it may take additional time to establish an effective antioxidant defense against the free radicals which accelerate prostate growth and worsen urinary issues.
Research suggests that 3 months of daily use helps significantly increase the likelihood of lasting improvement. Here is a reasonable timeline to expect:
Month 1: You may feel that you can more completely empty your bladder, allowing you to sleep longer through the night with fewer interruptions.
Month 2: You may notice a stronger urine stream, resulting in less dribbling and straining each time you visit the bathroom.
Month 3: Peak prostate support is reached. You may experience significantly fewer urinary urges both at night and during the day, better control over your bladder, and more confidence in the bedroom.
Tip: For best results, focus on consistency. Adding an effective prostate supplement to your daily routine for at least 3 months promotes exponential improvement, as each dose builds on the benefits of the last.
So, what characteristics distinguish top-tier prostate products from the rest of the pack?
The 5 Must-Have Ingredients for a Good Prostate Supplement
- Boron
Boron is a trace mineral that plays a key role in balancing hormones essential to prostate health. By supporting optimal levels of testosterone and reducing excess estrogen, boron helps shrink an enlarged prostate and relieve pressure on the urinary tract. This leads to better urine flow, reduced nighttime bathroom trips, and improved overall vitality in aging men.
- Tonkgat Ali
Tonkgat Ali is a medicinal root traditionally used in Southeast Asia, prized for its natural ability to support male hormone balance and vitality. Rich in bioactive compounds that help reduce cortisol and increase free testosterone, Tonkgat Ali works at the hormonal level to promote a healthier prostate, enhance libido, and ease urinary discomfort linked to age-related prostate changes.
- Achwagandha
The roots of the achwagandha plant, long revered in Ayurvedic medicine, contain a diverse blend of natural compounds that support hormone balance and stress reduction—two key factors in prostate health. Rich in withanolides and alkaloids, achwagandha helps counteract the hormonal imbalances and oxidative stress that contribute to prostate enlargement, while also promoting improved urinary flow and overall male vitality.
- Fenugreek
A traditional herb long used in Middle Eastern and South Asian medicine, fenugreek contains a rich concentration of steroidal saponins that help regulate male hormones linked to prostate function. These bioactive compounds have been shown to support healthy testosterone levels while reducing excess estrogen, creating a hormonal environment less favorable to prostate enlargement and more conducive to optimal urinary flow and bladder control.
- Nettle Root
Nettle root delivers a powerful combination of hormone-modulating and anti-inflammatory compounds that directly support prostate function. Like pumpkin seeds, it contains plant sterols that help inhibit the conversion of testosterone into DHT—a hormone closely linked to prostate enlargement. Additionally, nettle root supports stronger urine flow and improved bladder emptying, making it a key ally in relieving common urinary symptoms associated with an aging prostate.
Warning Signs of Potential Scams
- Lack of Clinical Studies
Be wary of companies that cite the clinical efficacy of individual ingredients within a product rather than the effectiveness of the product as a whole. The highest indicator of quality in a supplement is the commission of a placebo-controlled clinical study for safety and effectiveness by an independent third party. You expect the same high standard of research and testing before trusting a medication, so why would you not do the same before trusting a supplement?
- Filler Ingredients
There are very few natural ingredients for prostate relief that are both potent and safe for consumption. Other herbs and compounds that supposedly reduce urinary urges or improve bladder emptying have little clinical evidence to back their effectiveness. Watch out for supplements that include an extensive list of ingredients to create the illusion of comprehensive support. More is not necessarily better when it comes to your health. Some of the supplements we reviewed contained more than 10 unique ingredients!
Below, we break down our rankings and feature detailed reviews of the 5 best prostate supplements we analyzed, beginning with our top pick.
973 votes TOTAL RANKING
A+
Overall Grade
Pros
- Contains all 5 must-have ingredients
- No fillers or artificial additives
- Vegan, non-GMO, and gluten-free
- Made in the USA
Cons
The Bottom Line
We gave Prostafense our #1 ranking because it is the only prostate supplement that meets every one of our strict criteria.
Prostafense was clinically tested for safety and effectiveness over the course of 30 days in a placebo-controlled clinical trial conducted by Princeton Consumer Research. The study showed that people taking Prostafense experienced significantly fewer urinary urges and improved bladder emptying compared with placebo, allowing participants to sleep throughout the night without interruption.
Prostafense contains all 5 of the ingredients we consider essential for optimal prostate support, including a phytosterol complex standardized to 40 to 45% Boron, Tonkgat Ali, Achwagandha, Fenugreek, and Nettle Root. It is also produced in a GMP-certified laboratory in New York.
Although it appears on Amazon.com, we do not recommend purchasing it there, as the product is often sold by unauthorized third parties and may be counterfeit. The official version is only available through the manufacturer’s website.
Overall, Prostafense is our top pick for prostate health in 2025.
647 votes TOTAL RANKING
A-
Overall Grade
Pros
- Contains 4 out of 5 must-have ingredients
- No artificial additives
- Vegan, non-GMO, and gluten-free
- Made in the USA
Cons
- No clinical study
- Does not contain pumpkin seed
- Contains some ingredients with limited proof of efficacy
- Contains some ingredients with questionable efficacy and safety.
- May take longer to show noticeable results compared to similar products.
The Bottom Line
Super Beta Prostate Advanced contains 4 of the essential ingredients that we look for in an effective prostate support supplement, including boron, tonkgat ali, achwagandha, and fenugreek. However, it should be noted that the formula does not include a standardized phytosterol complex, which may limit its overall anti-inflammatory potential. Because nettle root is also missing, the product’s ability to support urinary flow and bladder emptying may be reduced.
To compensate for this, the formula includes L-arginine, beta-alanine, and quercetin—compounds commonly associated with cardiovascular and immune support. While these ingredients may offer general wellness benefits, clinical evidence supporting their role in prostate health remains limited. In particular, quercetin has shown some promise in lab studies, but more research is needed to confirm its effects in men with BPH.
The product has not been evaluated for safety and effectiveness in a placebo-controlled clinical study, which could justify the inclusion of general-purpose ingredients rather than a broader spectrum of targeted prostate antioxidants.
487 votes TOTAL RANKING
B-
Overall Grade
Pros
- Contains 4 out of 5 must-have ingredients
- No artificial additives
- Vegan, non-GMO, and gluten-free
- Made in the USA
Cons
- No clinical study
- Does not contain pumpkin seed
- Contains ingredients which use an outdated approach
The Bottom Line
Concentrated Ultra Prostagen by Metagenics includes 4 essential ingredients for a stronger stream:boron, tonkgat ali, achwagandha, and fenugreek. While boron is included, the formula does not include a standardized phytosterol complex, which may limit its overall anti-inflammatory potential.
Like Prostafense, Concentrated Ultra Prostagen includes the amino acid complex of L-arginine, beta-alanine, and quercetin. As indicated previously, these ingredients showed some benefit for participants in small-scale studies. However, the medical community’s clinical understanding of BPH, as well as statistical standards for efficacy, have changed dramatically since those trials.
Instead of nettle root, a natural ingredient known to support urinary flow and bladder emptying, this formula uses other compounds that may not provide the same prostate benefits.
Lastly, they have not tested the product for effectiveness in a clinical study.
4. Prostate FLO
429 votes TOTAL RANKING
C
Overall Grade
Pros
- Contains 2 out of 5 must-have ingredients
- No artificial additives
- Vegan, non-GMO, and gluten-free
- Made in the USA
Cons
- No clinical study
- Does not contain stinging nettle, lycopene, or pumpkin seed
- Contains ingredients with questionable efficacy
The Bottom Line
Prostate FLO by Xymogen features 2 of the most essential ingredients for prostate support, achwagandha and fenugreek, plus 4 other compounds to help reduce bladder urges.
The formula prominently contains achwagandha, which is traditionally used to reduce stress and support hormone balance. While achwagandha has shown benefits for general wellness, there is limited evidence supporting its direct effect on reducing urinary symptoms caused by an enlarged prostate.
The product also includes fenugreek, known for its hormone-regulating properties and potential to support prostate health. However, fenugreek alone may not be sufficient for comprehensive prostate support without key ingredients like nettle root or a phytosterol complex.
Perhaps most importantly, the product as a whole has not been tested by an independent, third-party clinical study.
Our Rating
C-
Overall Grade
Pros
- Contains 2 out of 5 must-have ingredients
- No artificial additives
- Non-GMO and gluten-free
- Made in the USA
Cons
- No clinical study
- May contain beta-sitosterol but lacks a standardized source
- Does not contain beta-sitosterol, lycopene, or pumpkin seed
The Bottom Line
Prostatrol Forte by Ortho Molecular Products contains boron and nettle root, both natural compounds known for their antioxidant and anti-inflammatory properties that may support prostate health. The formula also includes several minerals aimed at overall male wellness.
Unlike some supplements that combine ingredients to boost effectiveness, this product does not include tonkgat ali, a key herb shown to help balance hormones and reduce frequent urinary urges. While boron and nettle root offer some benefits, neither is standardized to provide a dedicated phytosterol complex, which plays a critical role in relieving common prostate symptoms.
With achwagandha and fenugreek missing from the formula, clinical studies would be necessary to confirm its effectiveness. Unfortunately, no such studies have been conducted for this product.
SUMMARY: TOP PRODUCT FOR 2025
973 votes TOTAL RANKING
A+
Overall Grade
For all products featured, results may vary. Please visit the product websites for further information.
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
The information on this website is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, we recommend you consult with a physician.
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